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Efficacy of citric acid and sodium hypochlorite as disinfectants against Mycoplasma bovis
Veterinary Microbiology ( IF 3.3 ) Pub Date : 2020-02-26 , DOI: 10.1016/j.vetmic.2020.108630
Sara Mahdizadeh , Kate Sawford , Mary van Andel , Glenn F. Browning

Mycoplasma bovis, a cattle pathogen of major economic importance across the globe, causes a range of diseases, including pneumonia and mastitis. Because of the limited options for effective treatment of these diseases, prevention and control are preferred to diagnosis and treatment. In this study, the efficacies of citric acid and sodium hypochlorite as disinfectants against M. bovis were tested using a modification of a standardised method for assessing the efficacy of disinfectants against bacteria. A citric acid concentration of 0.5% citric acid was found to be an effective disinfectant, reducing infectivity by close to 106 fold, while sodium hypochlorite at 1% was found to have similar efficacy to 0.5% citric acid. A 0.04% concentration of sodium hypochlorite was effective against M. bovis only in the absence of any organic material. Under these conditions, 0.25% citric acid found to have similar efficacy. These findings indicate that 0.5% citric acid or 1% sodium hypochlorite are likely to be effective disinfectants for M. bovis under field conditions and 0.04% sodium hypochlorite or 0.25% citric acid following removal of organic material.



中文翻译:

柠檬酸和次氯酸钠作为牛眼支原体消毒剂的功效

牛支原体是一种在全球具有重要经济意义的牛病原体,可引起多种疾病,包括肺炎和乳腺炎。由于有效治疗这些疾病的选择有限,因此预防和控制胜于诊断和治疗。在这项研究中,柠檬酸和次氯酸钠作为针对牛分枝杆菌的消毒剂的功效通过使用标准方法的改进方法进行了测试,以评估消毒剂对细菌的功效。发现柠檬酸浓度为0.5%的柠檬酸是有效的消毒剂,可将感染率降低近10 6。倍数,次氯酸钠含量为1%时与0.5%柠檬酸具有相似的功效。浓度为0.04%的次氯酸钠仅在没有任何有机物质的情况下才对牛分枝杆菌有效。在这些条件下,发现0.25%的柠檬酸具有相似的功效。这些发现表明,在田间条件下,0.5%的柠檬酸或1%的次氯酸钠很可能是牛分枝杆菌的有效消毒剂,去除有机物后,0.04%的次氯酸钠或0.25%的柠檬酸是有效的。

更新日期:2020-03-20
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