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Hunting Cells for Gentle Liberation
Cell Chemical Biology ( IF 8.6 ) Pub Date : 2020-03-19 , DOI: 10.1016/j.chembiol.2020.02.006
Günter Mayer , Tjasa Legen , Tejal Patwari , Anna Maria Weber

In a recent issue of Cell Chemical Biology, Gray et al. (2020) report an aptamer-based method to reversibly label and isolate EGF receptor-expressing cells from heterogeneous mixtures by cell sorting approaches. Subsequent treatment using complementary oligonucleotides restores full functionality of EGF receptors, highlighting the superiority of this method to antibody-based sorting.



中文翻译:

狩猎细胞温和解放

在最近的细胞化学生物学杂志中,Gray等。(2020)报道了一种基于适体的方法,通过细胞分选方法可逆地标记和分离异质混合物中的表达EGF受体的细胞。随后使用互补寡核苷酸进行的处理可恢​​复EGF受体的全部功能,从而突出了该方法相对于基于抗体的分选的优越性。

更新日期:2020-03-20
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