Frequently observed sleep/wake problems among pregnant women need comprehensive evaluation. This study was conducted to clarify the sleep/wake problems among pregnant women without gestational complications during the second and third trimester and the effects of sleep/wake problems on delivery outcomes. A total of 88 Japanese pregnant women participated in this study. In their second and third trimester, subjective sleep quality, insomnia severity, excessive daytime sleepiness (EDS), and restless legs syndrome/Willis-Ekbom disease (RLS/WED) were assessed using questionnaires; also, sleep disordered breathing (SDB) was screened using a pulse oximeter. From the second to the third trimester, an increasing tendency of sleep/wake problems was observed. During the third trimester, the percentages of women experiencing decreased subjective sleep quality, difficulty maintaining sleep (DMS), EDS, RLS/WED, and 3% oxygen desaturation index (ODI) values ≥5/h were 62.5, 45.5, 48.9, 9.1, and 29.5%, respectively. In a logistic regression analysis for EDS in the third trimester, the adjusted odds ratio (95% confidence interval) of total sleep duration < 6 h, moderate to severe DMS, and 3% ODI values ≥5/h were 3.25 (1.16–9.10), 4.74 (1.60–14.00), and 0.90 (0.28–2.89), respectively. Although short sleep durations, decreased subjective sleep quality, EDS, and SDB did not affect delivery outcomes or the infant’s condition, the percentage of women undergoing cesarean sections in the severe insomnia group was significantly higher (p = 0.008). Sleep/wake problems were frequent during pregnancy, especially during the third trimester. EDS among pregnant women was associated with shorter sleep durations and DMS rather than SDB. The effect of factors related to insomnia on delivery outcomes should thus be considered a crucial problem among pregnant Japanese women without gestational complications in clinical practice.

中文翻译：

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无妊娠并发症的日本孕妇睡眠/唤醒问题和分娩结局的特征

孕妇中经常观察到的睡眠/苏醒问题需要综合评估。进行这项研究的目的是弄清在妊娠中期和中期没有妊娠并发症的孕妇的睡眠/苏醒问题，以及睡眠/苏醒问题对分娩结局的影响。共有88名日本孕妇参加了这项研究。在他们的中期和中期，使用问卷调查评估主观睡眠质量，失眠严重程度，白天过度嗜睡（EDS）和不安腿综合征/ Willis-Ekbom疾病（RLS / WED）；同样，使用脉搏血氧仪对睡眠呼吸障碍（SDB）进行了筛查。从中期到中期，观察到睡眠/苏醒问题的增加趋势。在孕晚期，主观睡眠质量下降，难以维持睡眠（DMS），EDS，RLS / WED和3％氧饱和度指数（ODI）值≥5/ h的女性百分比分别为62.5、45.5、48.9、9.1和29.5％，分别。在妊娠中期EDS的logistic回归分析中，总睡眠时间<6 h，中度至重度DMS以及3％ODI值≥5/ h的校正比值比（95％置信区间）为3.25（1.16-9.10） ），4.74（1.60–14.00）和0.90（0.28–2.89）。尽管短暂的睡眠时间，主观睡眠质量下降，EDS和SDB均未影响分娩结局或婴儿状况，但严重失眠组剖宫产的妇女所占比例明显更高（p = 0.008）。怀孕期间经常出现睡眠/苏醒问题，尤其是在晚期。孕妇中的EDS与较短的睡眠时间和DMS而非SDB有关。因此，与失眠有关的因素对分娩结局的影响应被视为临床实践中没有妊娠并发症的日本孕妇中的关键问题。