BACKGROUND Melioidosis-associated peri-prosthetic infection is extremely rare. To date, melioidosis associated septic arthritis of the ankle joint following a medial malleolar internal fixation has not been reported. CASE PRESENTATION We describe a 49-year-old male with a history of long standing diabetes who presented with fever, constitutional symptoms and right ankle pain for 1 week. Ten years ago, he underwent a medial malleolar screw fixation following a traumatic closed fracture. His initial right ankle radiographs showed no evidence of osteomyelitis. He underwent a wound debridement and washout of the right ankle joint. The peripheral blood and pus from the ankle joint was culture positive for Burkholderia pseudomallei with very high antibody titres. His subsequent radiographs showed features of chronic osteomyelitis. He was treated with a prolonged course of antibiotics and repeated wound debridement. At follow up after 6 months, he had no clinical features of recurrent infection. CONCLUSIONS Melioidosis should be entertained in the differential diagnosis of peri-prosthetic infections in high risk patients.

中文翻译：

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内侧踝内固定后假肢伯克霍尔德菌假体周围感染：1例。

背景技术与类痔疮相关的假体周围感染极为罕见。迄今为止，还没有报道过踝内侧内固定后踝关节类oid病相关的脓毒性关节炎。病例介绍我们描述了一位49岁的男性，有长期的糖尿病史，出现发烧，体质症状和右脚踝疼痛1周。十年前，他在外伤性闭合性骨折后接受了内踝螺钉固定。他最初的右脚踝X光片未显示出骨髓炎的迹象。他进行了伤口清创术并洗净了右脚踝关节。踝关节的外周血和脓液对假苹果伯克霍尔德菌培养呈阳性，抗体滴度很高。他随后的放射照片显示了慢性骨髓炎的特征。他接受了长期的抗生素治疗并反复伤口清创。在六个月后的随访中，他没有再次感染的临床特征。结论对高危患者假体周围感染的鉴别诊断应考虑到类鼻疽。