Needle in a haystack : A fluorescence‐based peptide‐PNA hybrid beacon targeting the S100B protein, a biomarker for brain trauma, has been developed. The molecular beacon is capable of detecting nanomolar concentrations of S100B protein rapidly, even in the presence of serum. The design should be useful for developing molecular beacons for other protein biomarkers.

中文翻译：

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灵敏检测生物流体中蛋白质生物标志物的肽-PNA杂交信标。

大海捞针：针对S100B蛋白（一种脑外伤的生物标志物）的基于荧光的肽-PNA杂交信标已经开发出来。分子信标即使在存在血清的情况下也能够快速检测纳摩尔浓度的S100B蛋白。该设计对于开发其他蛋白质生物标记物的分子信标应该是有用的。