Background

Influenza infection causes substantial morbidity and mortality. However, little is known about hospital readmissions after an influenza hospitalization. The aim of our study was to characterize frequency of hospital readmissions among patients hospitalized with laboratory-confirmed influenza.

Methods

We conducted a retrospective study using Tennessee Emerging Infections Program Influenza Surveillance data from 2006 to 2016 and the concurrent TN Hospital Discharge Data System. We analyzed demographic characteristics and outcomes to better understand frequency and factors associated with hospital readmissions.

Results

Of the 2897 patients with a laboratory-confirmed influenza hospitalization, 409 (14%) and 1364 (47%) had at least one hospital readmission within 30 days and 1 year of the influenza hospitalization respectively. Multiple readmissions occurred in 739 patients (54%). The readmission group was older, female predominant, and had more comorbidities than patients not hospitalized. Pneumonia, acute COPD/asthma exacerbation, septicemia, acute respiratory failure, and acute renal failure were the most common causes for readmission at 30 days. Underlying cardiovascular disease, lung disease, kidney disease, diabetes, immunosuppression, and liver disease were associated with increased risk of readmission during the subsequent year.

Conclusions

After an admission with laboratory-confirmed influenza, there is a high likelihood of readmission within 30 days and 1 year adding to the morbidity of influenza.

中文翻译：

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实验室确认的流感住院后住院再入院。

背景

流感感染会导致大量发病和死亡。但是，对于流感住院后再次入院的情况知之甚少。我们研究的目的是确定在实验室确诊的流感住院患者中再次入院的频率。

方法

我们使用田纳西州新兴感染计划2006年至2016年的流感监测数据以及并发的TN医院出院数据系统进行了回顾性研究。我们分析了人口统计学特征和结局，以更好地了解与住院再入院相关的频率和因素。

结果

在2897名经过实验室确认的流感住院治疗的患者中，分别有409名（14％）和1364名（47％）在流感住院30天和1年内再次入院。739例患者中再次入院（54％）。再入院组年龄较大，女性为主，合并症多于未住院的患者。肺炎，急性COPD /哮喘急性发作，败血症，急性呼吸衰竭和急性肾衰竭是30天后再次入院的最常见原因。潜在的心血管疾病，肺部疾病，肾脏疾病，糖尿病，免疫抑制和肝脏疾病与随后一年再次入院的风险增加相关。

结论

实验室确诊的流感入院后，很可能在30天和1年内再次入院，增加了流感的发病率。