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Innate Cancer Immunoediting
Journal of Investigative Dermatology ( IF 6.5 ) Pub Date : 2020-03-19 , DOI: 10.1016/j.jid.2019.09.015
Tobias Bald , Mark J. Smyth

Immune cells detect and destroy cancer cells; however, very early changes in cancer genome and phenotype coupled with immune system selection cause escape variant survival in a process called cancer immunoediting. Although adaptive immunity is important for this process, the report by Kubick et al. provides novel insights into the role of innate immune cells for immunoediting of early transformed epithelial cells.



中文翻译:

先天性癌症免疫编辑

免疫细胞检测并破坏癌细胞;但是,癌症基因组和表型的早期变化以及免疫系统的选择会在称为癌症免疫编辑的过程中导致逃避变异的存活。尽管适应性免疫对于这一过程很重要,但Kubick等人的报告却指出。提供了有关先天免疫细胞对早期转化的上皮细胞进行免疫编辑的作用的新颖见解。

更新日期:2020-03-19
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