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Prospective analysis of cultures from the Furlow insertion tool: a possible etiology for penile prosthesis infections
International Journal of Impotence Research ( IF 2.6 ) Pub Date : 2020-03-18 , DOI: 10.1038/s41443-020-0256-2
Faysal A. Yafi , James Furr , Farouk M. El-Khatib , Koenraad van Renterghem , Luca Venturino , Robert Andrianne , Daniar Osmonov , David Ralph , Javier Romero Otero , Maxime Sempels , Georgios Hatzichristodoulou , Aaron Lentz , Steven K. Wilson

The most dreaded complication of penile prosthesis (PP) implantation is device infection. We sought to assess whether inadequate cleaning and sterilization of the reusable Furlow inserter may represent one of the last etiologies of infection in PP patients. We performed a prospective analysis of cultures of the Furlow inserter used for PP surgeries from seven centers between May 1st and June 30th, 2019. Once the Furlow was received for surgery, the surgical team inspected the device for assembly status (disassembled or not) and the presence of visible stains, pieces of tissue or discoloration on either the interior of the barrel or the plunger. Swab aerobic and anaerobic bacterial and fungal cultures were then obtained from the internal component, after removal from the external component if assembled, and after introduction and immediate removal from the external component if disassembled. A total of 83 Furlow devices were cultured. Median age of surgical instrument was 4 years (2–10 years). Methods of sterilization included autoclave, wet autoclave, steam, and Sterad. Median time from sterilization was 3 days (1–22). On initial presentation, 79 devices were disassembled (95.1%) and 4 devices were still assembled (4.9%). Three external components were discolored (3.6%), while internal components demonstrated two stains (2.4%) indicative of improper cleaning which were thought to be residual blood products. Overall, 2/83 (2.4%) devices revealed positive swab cultures for Staphylococcus epidermidis. Swab cultures were negative for fungi and anaerobic bacteria. This patient cohort will continue to be followed to see if device infection occurs but it is unlikely to be meaningful since contaminated Furlows were discarded. Improper cleaning and/or sterilization of the Furlow Insertion Instrument may represent a source of infection for patients undergoing PP implantation.



中文翻译:

使用Furlow插入工具对培养物进行前瞻性分析:阴茎假体感染的可能病因

阴茎假体(PP)植入最可怕的并发症是装置感染。我们试图评估可重复使用的Furlow插入器的清洁和消毒不足是否可能代表PP患者的最后感染病因之一。我们对2019年5月1日至6月30日期间来自七个中心的用于PP手术的Furlow插入器的文化进行了前瞻性分析。收到Furlow进行手术后,手术团队检查了该设备的组装状态(是否拆卸)以及枪管内部或柱塞内部是否存在可见的污渍,组织碎片或变色。然后从内部组件中获得拭子好氧,厌氧细菌和真菌培养物,如果从外部组件中取出拭子,并在引入后立即拆卸,如果要拆卸则从外部组件中取出。共培养了83个Furlow装置。手术器械的中位年龄为4岁(2-10岁)。灭菌方法包括高压灭菌器,湿式高压灭菌器,蒸汽和Sterad。灭菌的中位时间为3天(1-22)。最初展示时,拆解了79台设备(占95.1%),仍组装了4台设备(占4.9%)。三个外部组件变色(3.6%),而内部组件显示两个污渍(2.4%)表明清洁不当,被认为是残留的血液产品。总体而言,2/83(2.4%)的设备显示拭子培养阳性 灭菌方法包括高压灭菌器,湿式高压灭菌器,蒸汽和Sterad。灭菌的中位时间为3天(1-22)。最初展示时,拆解了79台设备(占95.1%),而仍组装了4台设备(占4.9%)。三个外部组件变色(3.6%),而内部组件显示两个污渍(2.4%)表明清洁不当,被认为是残留的血液产品。总体而言,2/83(2.4%)的设备显示拭子培养阳性 灭菌方法包括高压灭菌器,湿式高压灭菌器,蒸汽和Sterad。灭菌的中位时间为3天(1-22)。最初展示时,拆解了79台设备(占95.1%),仍组装了4台设备(占4.9%)。三个外部组件变色(3.6%),而内部组件显示两个污渍(2.4%)表明清洁不当,被认为是残留的血液产品。总体而言,2/83(2.4%)的设备显示拭子培养阳性 4%)表示清洁不当,被认为是残留的血液产品。总体而言,2/83(2.4%)的设备显示拭子培养阳性 4%)表示清洁不当,被认为是残留的血液产品。总体而言,2/83(2.4%)的设备显示拭子培养阳性表皮葡萄球菌。拭子培养物对真菌和厌氧菌呈阴性。将继续追踪该患者队列,以查看是否发生了设备感染,但是由于被污染的Furlows被丢弃了,因此这不太有意义。Furlow插入器械的不当清洁和/或灭菌可能代表接受PP植入的患者的感染源。

更新日期:2020-04-24
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