Near-IR fluorescence imaging (NIRFI) is a highly promising technique for improving cancer theranostics in the era of precision medicine. Through the combination with cutting-edge bionanotechnologies, the potential of NIRFI can be greatly broadened. A variety of novel NIRF nanoprobes has been developed with ultimate goals of addressing unmet medical needs. Here, we present recent breakthroughs on the fundamental aspects of NIRFI, such as imaging at long wavelengths (1000-1700 nm), and the use of new approaches (X-rays, chemiluminescence, radioluminescence, etc.) for the excitation of novel nanoprobes. Within two decades, research on NIRF nanoprobes has translated to clinical trials and it will further translate to cancer management.

中文翻译：

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用于癌症分子成像的NIRF纳米探针：临诊诊所。

近红外荧光成像（NIRFI）是在精密医学时代改善癌症治疗学的一项很有前途的技术。通过与最先进的生物纳米技术相结合，NIRFI的潜力可以大大扩展。已经开发出多种新颖的NIRF纳米探针，其最终目的是解决未满足的医疗需求。在这里，我们介绍了近红外技术的基本方面的最新突破，例如长波长（1000-1700 nm）成像，以及使用新方法（X射线，化学发光，放射致发光等）激发新型纳米探针。 。在二十年内，有关NIRF纳米探针的研究已转化为临床试验，并将进一步转化为癌症治疗。