High incidence of treatable oral conditions has been reported among palliative patients. However, a large proportion of palliative patients lose their ability to communicate their sufferings. Therefore, it may lead to under-reporting of oral conditions among these patients. This review systematically synthesized the published evidence on the presence of oral conditions among palliative patients, the impact, management, and challenges in treating these conditions. An integrative review was undertaken with defined search strategy from five databases and manual search through key journals and reference list. Studies which focused on oral conditions of palliative patients and published between years 2000 to 2017 were included. Xerostomia, oral candidiasis and dysphagia were the three most common oral conditions among palliative patients, followed by mucositis, orofacial pain, taste change and ulceration. We also found social and functional impact of having certain oral conditions among these patients. In terms of management, complementary therapies such as acupuncture has been used but not well explored. The lack of knowledge among healthcare providers also posed as a challenge in treating oral conditions among palliative patients. This review is first in its kind to systematically synthesize the published evidence regarding the impact, management and challenges in managing oral conditions among palliative patients. Although there is still lack of study investigating palliative oral care among specific group of patients such as patients with dementia, geriatric or pediatric advanced cancer patients, this review has however provided baseline knowledge that may guide health care professionals in palliative settings.

中文翻译：

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姑息和绝症患者的口腔健康问题：全面的系统评价。

据报道，姑息患者可治疗的口腔疾病发生率很高。但是，许多姑息性患者失去了交流痛苦的能力。因此，这可能导致这些患者的口腔状况报告不足。这篇综述系统地综合了有关姑息患者口腔疾病的存在，治疗这些疾病的影响，管理和挑战的公开证据。对来自五个数据库的明确搜索策略进行了全面审查，并通过关键期刊和参考文献列表进行了手动搜索。研究包括2000年至2017年间发表的针对姑息性患者口腔疾病的研究。口干症，口腔念珠菌病和吞咽困难是姑息患者中最常见的三种口腔疾病，其次是粘膜炎，口面部疼痛，味觉改变和溃疡。我们还发现这些患者中某些口腔条件对社会和功能的影响。在管理方面，已经使用了辅助疗法，例如针灸，但尚未得到很好的探索。医疗保健提供者之间缺乏知识也对姑息患者的口腔疾病构成了挑战。该综述是首次系统地综合有关姑息患者口腔疾病管理中的影响，管理和挑战的公开证据。尽管仍缺乏针对特定患者群体（例如痴呆症患者，老年或儿科晚期癌症患者）进行姑息性口腔护理的研究，