Fluorescent pH‐sensitive probes have been trapped in the lumen of liposomes. The sensor is linked to a DNA oligomer that is complementary to a second oligomer with a lipophilic moiety to anchor the DNA conjugate to the inner and outer leaflets of the lipid bilayer. The DNA scaffold allows subsequent selective removal of the probe in the outer bilayer leaflet.

中文翻译：

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双功能DNA双链体允许将pH探针有效掺入脂质体中。

荧光pH敏感探针已被困在脂质体的内腔中。该传感器与DNA低聚物连接，该DNA低聚物与具有亲脂性部分的第二低聚物互补，以将DNA缀合物锚定在脂质双层的内部和外部小叶上。DNA支架允许随后选择性除去外双层小叶中的探针。