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Circular Nucleic Acids: Discovery, Functions and Applications.
ChemBioChem ( IF 3.2 ) Pub Date : 2020-03-16 , DOI: 10.1002/cbic.202000003
Jiuxing Li 1 , Mostafa Mohammed-Elsabagh 1 , Freeman Paczkowski 1 , Yingfu Li 1
Affiliation  

Going round again : Owing to their unique topological structures, biological stability, and ease of coupling with rolling circle amplification for the synthesis of a long, single‐stranded product with tandem repeats, circular nucleic acids have been extensively applied in diagnosis, therapy, and bio‐nanotechnology. Progress in the discovery, construction, and applications of circular nucleic acids is reviewed.
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中文翻译:

环状核酸:发现,功能和应用。

再次循环:由于其独特的拓扑结构,生物学稳定性以及与滚环扩增的耦合容易性,可合成具有串联重复序列的长单链产物,因此环状核酸已广泛应用于诊断,治疗和生物纳米技术。综述了环状​​核酸的发现,构建和应用方面的进展。
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更新日期:2020-03-16
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