The development of a universal coating strategy for the construction of functional surfaces and modulation of surface properties is of great research interest. Tannic acid (TA) could serve as a sole precursor for the deposition of colorless coatings on substrate surfaces. However, the deposition of TA requires a high salt concentration (0.6 M), which may limit its practical application. Herein, primary amine moieties were introduced on the gallic acid groups in TA. The resultant amine-containing TA derivative (TAA) can self-polymerize under mild conditions (10 mM, Tris buffer), and form uniform and colorless coatings in a material-independent manner. In comparison with the TA coating under the same preparation conditions, the TAA coating exhibits an increased thickness as measured by ellipsometry. The TAA coating is adapted for secondary surface functionalization. The hydrophilic mPEG brushes can be grafted on the TAA coating to inhibit non-specific protein adsorption. A biotin probe can be immobilized on the TAA coating to promote specific binding with avidin. In addition, the TAA coating can be utilized for in situ reduction of silver ions to AgNPs. The resulting AgNP-loaded TAA coating can inhibit bacterial adhesion and prevent biofilm formation.

中文翻译：

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用于多功能表面改性的含氨基鞣酸衍生物介导的通用涂料

开发用于功能性表面的构造和表面性质的调节的通用涂层策略具有很大的研究兴趣。单宁酸（TA）可以用作在基材表面上沉积无色涂层的唯一前体。但是，TA的沉积需要高盐浓度（0.6 M），这可能会限制其实际应用。在此，伯胺部分被引入TA中的没食子酸基团上。所得的含胺TA衍生物（TAA）可以在温和条件下（10 mM，Tris缓冲液）自聚合，并以与材料无关的方式形成均匀无色的涂层。与在相同制备条件下的TA涂层相比，TAA涂层表现出增加的厚度，如通过椭圆光度法测量的。TAA涂层适用于二次表面功能化。可以将亲水性mPEG刷子移植到TAA涂层上，以抑制非特异性蛋白质的吸附。可将生物素探针固定在TAA涂层上，以促进与抗生物素蛋白的特异性结合。此外，TAA涂层可用于将银离子原位还原为AgNPs。所得的载有AgNP的TAA涂层可抑制细菌粘附并防止生物膜形成。