A paper-based surface enhanced Raman scattering (SERS) sensor with synergistic enhancement strategy for selective detection of tartrazine in food products has been established in this work. For economic and mass production purposes, paper substrates were firstly installed with a silver layer to endow the paper with electroconductibility and dense plasmonic hotspots. A biomimetic recognizer (BR) membrane was attached upon the Ag paper as specific identification device, and a layer of high-density of silver nanoparticles (AgNPs) was decorated on the surface of Ag/BR paper through in-situ growth method to form a sandwich structure. Since the double layer of Ag/AgNPs demonstrated excellent local plasma resonance effect, combined with the identification function of BR, it made the paper SERS sensor emerge incredible Raman synergistic enhancement response on tartrazine molecules embraced the plasma nanoparticles. Thus, the synergistically enhanced Ag/BR/AgNPs paper SERS sensor was achieved and applied in on-site test of tartrazine in Children's snacks. The linear range (0.3∼10 μg mL^-1) and the limit of detection (0.1138 μg mL^-1) of the SERS paper strip could be applied as a screening or occupational cut-off of tartrazine (100 μg mL^-1) for reference. In addition, the proposed paper sensor can be a potential candidate for multicomponent screening and is suitable for mass production and promotion.

这项工作建立了一种基于纸的表面增强拉曼散射（SERS）传感器，该传感器具有协同增强策略，可选择性检测食品中的酒石黄。为了经济和批量生产，首先在纸质基材上安装了一层银层，以赋予纸质导电性和密集的等离子体热点。将仿生识别器（BR）膜附着在Ag纸上作为特定的识别装置，并通过原位生长方法在Ag / BR纸的表面上装饰一层高密度的银纳米颗粒（AgNPs），形成一层三明治结构。由于双层Ag / AgNPs表现出优异的局部等离子体共振效应，再加上BR的识别功能，它使纸质SERS传感器对包裹在血浆纳米颗粒上的酒石azine分子产生了不可思议的拉曼协同增强反应。因此，获得了协同增强的Ag / BR / AgNPs纸质SERS传感器，并将其应用于儿童零食中酒石黄的现场测试。线性范围（0.3〜10μgmL^-1）和检测（0.1138微克毫升的极限^-1的SERS纸条的）可以作为筛选或职业截止柠檬黄（100微克毫升施加^-1）以供参考。另外，所提出的纸传感器可以是用于多组分筛选的潜在候选者，并且适合于批量生产和推广。