Noncanoncial inflammasome activation by cytosolic lipopolysaccharide (LPS) causes pyroptotic cell death facilitated by gasdermin D (GSDMD) pore formation. In this issue of Immunity, Huang et al. describe how cytosolic LPS in endothelial cells does not cause cell death but restrains endothelial cell proliferation.

中文翻译：

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线粒体GSDMD毛孔DAMPen发烧。

胞质脂多糖（LPS）引起的非规范性炎症小体激活会导致由胃泌素D（GSDMD）孔促成的焦细胞凋亡。在《免疫》一期中，Huang等人。描述了内皮细胞中的胞质脂多糖如何不会引起细胞死亡，而是抑制内皮细胞增殖。