A mild and cost-effective decarboxylation cyclization method was developed for the synthesis of chiral 5-substituted thiazolidine-2-thione derivatives from β-amino oxazolidinones. This reaction was mediated by CS₂ and allowed a highly stereoselective synthesis of linezolid thiazolidine-2-thione derivatives. The chirality of the linezolid base was completely retained in the final product.

中文翻译：

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通过CS ₂介导的脱羧环化反应不对称合成利奈唑胺噻唑烷-2-硫酮衍生物

开发了一种温和且经济有效的脱羧环化方法，用于从β-氨基恶唑烷酮合成手性5取代的噻唑烷-2-硫酮衍生物。该反应是由CS ₂介导的，可以高度立体选择性地合成利奈唑胺噻唑烷-2-硫酮衍生物。利奈唑胺碱的手性完全保留在最终产物中。