Osteoporosis (OP) is a systemic metabolic bone disorder identified as an essential health issue worldwide. Orthopedic imaging approaches were commonly used with some limitations. Thus, our study aimed to investigate the diagnostic value of magnetic resonance spectroscopy (1-H MRS) and m-Dixon-Quant in OP. A total of 76 subjects were enrolled in the study and bone mineral density (BMD) was measured using quantitative computed tomography (QCT). Then, the subjects were divided into three groups according to BMD: normal control group, osteopenia group and OP group. The following parameters were recorded for each patient: gender, age, height, body weight, waist circumference, and hip circumference. Further, the fat fraction percentage (FF%) values were determined by 1-H MRS and m-Dixon-Quant methods. In both 1-H MRS and magnetic resonance Imaging (MRI) m-Dixon-Quant, the FF% exhibited a negative correlation with BMD (P < 0.05). The FF% value of the OP group was significantly higher than that of the control group (P < 0.05). In addition, the FF% value in the m-Dixon scans was positively related to age, while BMD showed a negative linear relationship with age (P < 0.0001). Further, females had a significantly higher FF% value compared to males (P < 0.01), and height was correlated with BMD (P < 0.05) but not with FF% (P > 0.05). MRI investigations especially FF% value in the m-Dixon-Quant imaging system is correlated with OP. Its diagnostic value remains to be demonstrated on a large prospective cohort of patients. Besides, parameters such as age, gender, and height are important factors for predicting and diagnosing OP.

中文翻译：

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磁共振成像中的脂肪百分比：提高骨质疏松症检测参数

骨质疏松症（OP）是一种全身性代谢性骨病，已被确定为全球范围内的重要健康问题。骨科影像学检查方法通常存在一些局限性。因此，我们的研究旨在探讨磁共振波谱（1-H MRS）和m-Dixon-Quant在OP中的诊断价值。该研究共纳入76名受试者，并使用定量计算机断层扫描（QCT）测量了骨矿物质密度（BMD）。然后，根据BMD将受试者分为三组：正常对照组，骨质减少组和OP组。为每个患者记录以下参数：性别，年龄，身高，体重，腰围和髋围。此外，通过1-H MRS和m-Dixon-Quant方法确定脂肪分数百分比（FF％）值。在1-H MRS和磁共振成像（MRI）m-Dixon-Quant中，FF％与BMD呈负相关（P <0.05）。OP组的FF％值显着高于对照组（P <0.05）。此外，m-Dixon扫描中的FF％值与年龄呈正相关，而BMD与年龄呈负线性关系（P <0.0001）。此外，女性的FF％值比男性高（P <0.01），身高与BMD相关（P <0.05），而与FF％不相关（P> 0.05）。MRI检查，特别是m-Dixon-Quant成像系统中的FF％值与OP相关。其诊断价值仍有待在大量的前瞻性队列研究中得到证实。此外，年龄，性别和身高等参数也是预测和诊断OP的重要因素。