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Killing cancer cells by rupturing their lysosomes.
Nature Nanotechnology ( IF 38.3 ) Pub Date : 2020-04-01 , DOI: 10.1038/s41565-020-0639-z
Jichuan Qiu 1 , Younan Xia 1, 2
Affiliation  

Nanoparticles covered with a mix of positively and negatively charged ligands aggregate into supraparticles in the lysosomes of cancer cells, disrupting the integrity of the lysosomal membrane and killing the cells without involving any anticancer drugs.

中文翻译:

通过破坏它们的溶酶体杀死癌细胞。

覆盖有带正电荷和带负电荷的配体的纳米颗粒在癌细胞的溶酶体中聚集到超颗粒中,破坏了溶酶体膜的完整性并杀死细胞,而没有涉及任何抗癌药物。
更新日期:2020-03-16
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