Sex as a biological variable (SABV) is critical for understanding the broad range of physiological, neurobiological, and behavioral consequences of early life adversity(ELA). The study of the interaction of SABV and ELA ties into several current debates, including the importance of taking into account SABV in research, differing strategies employed by males and females in response to adversity, and the possible evolutionary and developmental mechanisms of altered development in response to adversity. This review highlights the importance of studying both sexes, of understanding sex differences (and similarities) in response to ELA, and provides a context for the debate surrounding whether the response to ELA may be an adaptive process.

中文翻译：

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综合观点以了解应对早年逆境时的性别差异

性别作为生物变量 (SABV) 对于了解早期生活逆境 (ELA) 的广泛生理、神经生物学和行为后果至关重要。SABV 和 ELA 相互作用的研究与当前的几个争论有关，包括在研究中考虑 SABV 的重要性、男性和女性在应对逆境时采用的不同策略，以及响应改变发展的可能进化和发展机制到逆境。这篇综述强调了研究两性、理解对 ELA 的反应的性别差异（和相似性）的重要性，并为围绕对 ELA 的反应是否可能是一个适应性过程的辩论提供了背景。