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Ageotypes: Distinct Biomolecular Trajectories in Human Aging.
Trends in Pharmacological Sciences ( IF 13.8 ) Pub Date : 2020-03-16 , DOI: 10.1016/j.tips.2020.02.003
Brian D Piening 1 , Jennifer Lovejoy 2 , John C Earls 3
Affiliation  

Many studies have demonstrated that biological age (BA) varies significantly among individuals of similar chronological age. A recent study by Ahadi et al. used longitudinal and deep multi-omic profiling to identify individuals with distinct BA phenotypes or 'ageotypes'. These ageotypes open new avenues to creating diagnostic and treatment strategies that may slow the aging process based on the unique biochemistry of each individual.

中文翻译:

年龄型:人类衰老中不同的生物分子轨迹。

许多研究表明,年龄相似的个体之间的生物学年龄(BA)差异很大。Ahadi等人的最新研究。使用纵向和深度多组学分析来鉴定具有不同BA表型或“基因型”的个体。这些陈规定型为建立诊断和治疗策略开辟了新途径,这些策略可能会根据每个人独特的生物化学来减缓衰老过程。
更新日期:2020-03-16
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