While in the general paediatric population the presence of abnormal lipid values is estimated at 8–20%, depending on the population, accepted norms and age, it was shown that in the population of lean children the prevalence of dyslipidemia is lower than in obese children, in whom it ranges from 20 to over 40%. Until now, however, no results of similar studies on a large sample of children form a Central or Eastern European country have been published. The aim of this study was to evaluate the prevalence of lipid disorders in overweight and obese children and adolescents participating in an integrated weight reduction programme. According to the “6-10-14 for Health” programme implementation schedule, the programme accepted patients living in Gdańsk, aged 6, 9–11 and 14 years old, with BMI above the 85th percentile for age and sex, according to the Polish percentile charts. During the first visit, each of the participants underwent basic anthropometric examinations - body weight, body height, waist and hip circumference, blood pressure and body composition by bioelectrical impedance were measured. Blood samples were taken to assess lipid, glucose and insulin levels as well as alanine transaminase (ALT) and thyroid stimulating hormone (TSH) activity. 1948 patients underwent full anthropomethric and blood work measurements. At least one of the lipid disorders occurred in 38.23% of girls and 40.51% of boys with overweight and obesity. The most common lipid disorderswere decreased high-density lipoprotein cholesterol (HDL-C) levels (present in 20.55% of the girls and 23.79% of the boys) and elevated low-density lipoprotein cholesterol (LDL-C) (present in 15.31% of the girls and 14.25% of the boys). There was no strong association between lipid disorders and age, sex, birth weight, gestational age at birth or body composition. Such a frequent occurrence of lipid disorders in the population of children and adolescents should be an important warning signal both at the individual and population level. Not only effective screening methods for overweight and obese children should be implemented from an early age but also therapeutic measures are required. The trial is registered under the Local Ethics Committee at Medical University of Gdańsk, decision No. NKBBN/228/2012 from 25 June 2012.

中文翻译：

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超重和肥胖儿童的血脂异常-来自波兰的大型队列研究

虽然在一般的儿科人群中，根据人群，公认的规范和年龄，血脂异常值估计为8％至20％，但研究表明，在肥胖儿童中，血脂异常的患病率低于肥胖儿童。 ，其中20％到40％以上。但是，到目前为止，尚未发表对中欧或东欧国家的大量儿童进行类似研究的结果。这项研究的目的是评估参与一项综合减肥计划的超重和肥胖儿童和青少年中脂质疾病的患病率。根据“ 6-10-14促进健康”计划的实施时间表，该计划接受了6、9-11和14岁年龄在格但斯克的BMI年龄和性别高于85％的患者，根据波兰百分位图。在第一次访问期间，每个参与者都接受了基本的人体测量学检查-通过生物电阻抗测量了体重，身高，腰围和臀围，血压和身体成分。采集血液样本以评估血脂，葡萄糖和胰岛素水平以及丙氨酸转氨酶（ALT）和甲状腺刺激激素（TSH）的活性。1948年患者接受了完整的人体除法和血液检查。超重和肥胖的女孩中至少有一种血脂异常发生在38.23％的女孩和40.51％的男孩中。最常见的脂质疾病是高密度脂蛋白胆固醇（HDL-C）水平降低（在20.55％的女孩中和23.79％的男孩中）和低密度脂蛋白胆固醇（LDL-C）升高（在15岁中）。31％的女孩和14.25％的男孩）。脂质疾病与年龄，性别，出生体重，出生时的胎龄或身体组成之间无密切关联。在儿童和青少年人群中血脂异常的频繁发生，无论是在个人还是在人群水平上，均应成为重要的预警信号。不仅应该从小就实施针对超重和肥胖儿童的有效筛查方法，还需要治疗措施。该试验已于2012年6月25日在格但斯克医科大学地方伦理委员会注册，决定号为NKBBN / 228/2012。在儿童和青少年人群中血脂异常的频繁发生，无论是在个人还是在人群水平上，均应成为重要的预警信号。不仅应该从小就实施针对超重和肥胖儿童的有效筛查方法，还需要治疗措施。该试验已于2012年6月25日在格但斯克医科大学地方伦理委员会注册，决定号为NKBBN / 228/2012。在儿童和青少年人群中血脂异常的频繁发生，无论是在个人还是在人群水平上，均应成为重要的预警信号。不仅应该从小就实施针对超重和肥胖儿童的有效筛查方法，还需要治疗措施。该试验已于2012年6月25日在格但斯克医科大学地方伦理委员会注册，决定号为NKBBN / 228/2012。