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Research progress in the application of in situ hydrogel system in tumor treatment
Drug Delivery ( IF 6 ) Pub Date : 2020-03-13 , DOI: 10.1080/10717544.2020.1739171
Weipeng Wei 1, 2, 3 , Hongfang Li 1, 2, 3 , Chengchen Yin 1, 2, 3 , Fushan Tang 1, 2, 3
Affiliation  

Abstract

The in situ hydrogel drug delivery system is a hot research topic in recent years. Combining both properties of hydrogel and solution, in situ hydrogels can provide many advantages for drug delivery application, including easy application, high local drug concentration, prolonged drug retention time, reduced drug dose in vivo, good biocompatibility and improved patient compliance, thus has potential in tumor treatment. In this paper, the related literature reports in recent years were reviewed to summarize and discuss the research progress and development prospects in the application of in situ hydrogels in tumor treatment.



中文翻译:

原位水凝胶系统在肿瘤治疗中应用的研究进展

摘要

原位水凝胶药物递送系统是近年来的研究热点。原位水凝胶结合了水凝胶和溶液的两种特性,可以为药物递送应用提供许多优势,包括使用方便、局部药物浓度高、药物保留时间长、减少体内药物剂量、良好的生物相容性和提高患者依从性,因此具有潜力在肿瘤治疗中。本文综述了近年来的相关文献报道,对原位水凝胶在肿瘤治疗中应用的研究进展和发展前景进行了总结和探讨。

更新日期:2020-04-20
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