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Cortical Response to Fat Taste.
Chemical Senses ( IF 3.5 ) Pub Date : 2020-05-21 , DOI: 10.1093/chemse/bjaa019
Camilla Arndal Andersen 1, 2 , Line Nielsen 1 , Stine Møller 1 , Preben Kidmose 2
Affiliation  

We sense fat by its texture and smell, but it is still unknown whether we also taste fat despite evidence of both candidate receptors and distinct fat taste sensations. One major reason fat is still not recognized as a basic taste quality is that we first need to demonstrate its underlying neural activity. To investigate such neural fat taste activation, we recorded evoked responses to commercial cow milk products with 0.1%, 4%, and 38 % fat via high-density electroencephalography (EEG) from 24 human participants. The experimental design ensured that the products would only be discriminable via their potential fat taste; all stimuli were carefully controlled for differences in viscosity, lubrication, odor, temperature, and confounding tastes (sweetness, acidity, and "off-taste") and were delivered directly onto the tongue using a set of computer-controlled syringe pumps. Advanced topographical pattern analysis revealed different neural activation to the milk products 85-134 ms after stimulus onset, which, as expected, best discriminated the two milk fat extremes (0.1% and 38% fat). Notably, this time period has previously been shown to also encode basic taste qualities, such as sweet or salty. By adding to the evidence of cortical fat taste processing in response to staple food, our finding not only substantiates that we taste fat but also highlights its potential relevance during our everyday lives with possible large-scale impacts on motivational eating behavior to explain overconsumption of energy-dense foods.

中文翻译:

皮质对脂肪味的反应。

我们通过脂肪的质地和气味来感知脂肪,但是尽管有候选受体和明显的脂肪味觉的证据,我们是否也能品尝到脂肪仍是未知的。仍然没有将脂肪视为基本口味品质的一个主要原因是,我们首先需要证明其潜在的神经活动。为了研究这种神经脂肪味的激活,我们通过高密度脑电图(EEG)记录了来自24位受试者的对商业含0.1%,4%和38%脂肪的牛奶产品的诱发反应。实验设计确保只能通过其潜在的脂肪味道来区分产品。仔细控制所有刺激物的粘度,润滑,气味,温度和混杂口味(甜度,酸度和“异味”)的差异 ),然后使用一组计算机控制的注射泵将其直接递送到舌头上。先进的地形图分析显示,在刺激发作后85-134毫秒,乳制品具有不同的神经激活作用,正如预期的那样,这可以最好地区分两种极端的乳脂(0.1%和38%的脂肪)。值得注意的是,该时间段以前已显示出还编码基本的味道品质,例如甜或咸。通过增加对主食做出反应的皮质脂肪口味加工的证据,我们的发现不仅证实了我们对脂肪的口味,还强调了其在日常生活中的潜在意义,可能对动机性饮食行为产生大规模影响,以解释能量的过度消费密集的食物。先进的地形图分析显示,在刺激发作后85-134毫秒,乳制品具有不同的神经激活作用,正如预期的那样,这可以最好地区分两种极端的乳脂(0.1%和38%的脂肪)。值得注意的是,该时间段以前已显示出还编码基本的味道品质,例如甜或咸。通过增加对主食做出反应的皮质脂肪口味加工的证据,我们的发现不仅证实了我们对脂肪的口味,还强调了其在日常生活中的潜在意义,可能对动机性饮食行为产生大规模影响,以解释能量的过度消费密集的食物。先进的地形图分析显示,在刺激发生后85-134毫秒,乳制品具有不同的神经激活,正如预期的那样,可以最好地区分两种极端的乳脂(0.1%和38%的脂肪)。值得注意的是,该时间段以前已显示出还编码基本的味道品质,例如甜或咸。通过增加对主食的皮质脂肪味觉处理的证据,我们的发现不仅证实了我们对脂肪的味觉,而且还突出了其在日常生活中的潜在意义,并可能对动机性饮食行为产生大规模影响,以解释能量的过度消费密集的食物。先前已证明此时间段还编码基本的味道品质,例如甜或咸。通过增加对主食做出反应的皮质脂肪口味加工的证据,我们的发现不仅证实了我们对脂肪的口味,还强调了其在日常生活中的潜在意义,可能对动机性饮食行为产生大规模影响,以解释能量的过度消费密集的食物。先前已证明此时间段还编码基本的味道品质,例如甜或咸。通过增加对主食做出反应的皮质脂肪口味加工的证据,我们的发现不仅证实了我们对脂肪的口味,还强调了其在日常生活中的潜在意义,可能对动机性饮食行为产生大规模影响,以解释能量的过度消费密集的食物。
更新日期:2020-03-14
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