Frailty affects the quality of life of older age adults by limiting mobility, reducing physiological reserve and reducing independence. The frailty phenotype is typically characterised by exhaustion, loss or lack of physical activity, weight loss and weakness, although more recently there have been proposals to extend the frailty criteria to include physiological characteristics such as inflammation, oxidative stress and vascular function. Exercise has the potential to prevent, delay or even reverse frailty, but not all exercise is perceived as suitable for an older age population. The purpose of this study was to test Tai Chi and Zumba Gold® as exercise interventions in older age adults (65 to 75 years old) to improve characteristics related to the frailty phenotype. Muscle strength and flexibility (functional fitness as a measure of weakness), cardiorespiratory fitness, blood pressure, vascular function (FMD), markers of oxidative stress (total antioxidant capacity, malondialdehyde, 8-isoprostane, protein carbonyl), inflammation (CRP) and aspects of wellbeing related to exhaustion were assessed at baseline (pre-), 6 weeks (mid-) and 12 weeks (post-intervention). Both Tai Chi and Zumba Gold® improved systolic blood pressure, vascular function, and functional fitness following the 12 week intervention to a similar extent. Furthermore Antioxidant capacity was significantly increased (303 ± 15.56 vs. 336 ± 18.82 μm; p = 0.0028) and lipid oxidation significantly reduced (36.41 ± 6.4 vs 13.49 ± 2.5 pg/ml; p = 0.0042) after 12 weeks of Tai Chi compared to baseline. Anxiety, physical and mental fatigue decreased in both groups, with a greater decrease in mental fatigue in the Tai Chi group. Taken together, these changes suggest that Tai Chi has the potential to reduce outcomes related to the extended frailty phenotype in older age adults.

中文翻译：

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太极拳是一种有效的运动形式，可以减少老年人的衰弱迹象。

身体虚弱会限制活动能力，减少生理储备并降低独立性，从而影响老年人的生活质量。脆弱的表型通常以体力消耗，缺乏或缺乏体育活动，体重减轻和虚弱为特征，尽管最近有人提出将脆弱的标准扩展到包括诸如炎症，氧化应激和血管功能的生理特征。运动有可能预防，延缓甚至逆转身体虚弱，但并非所有运动都被认为适合老年人群。这项研究的目的是测试太极拳和尊巴舞金牌作为对老年人（65至75岁）的运动干预措施，以改善与体弱表型有关的特征。肌肉力量和柔韧性（功能适应性作为无力的度量），在基线前（评估前）评估了心肺健康，血压，血管功能（FMD），氧化应激指标（总抗氧化能力，丙二醛，8-异前列腺素，羰基蛋白），炎症（CRP）和与体力消耗有关的健康方面，6周（中期）和12周（干预后）。经过12周的干预后，太极拳和ZumbaGold®均可改善收缩压，血管功能和功能适应性。此外，与太极拳相比，太极拳12周后抗氧化能力显着提高（303±15.56 vs. 336±18.82μm； p = 0.0028），脂质氧化显着降低（36.41±6.4 vs 13.49±2.5 pg / ml； p = 0.0042）。基线。两组的焦虑，身体和精神疲劳均降低，而太极组的精神疲劳降低幅度更大。