Intermolecular strain has long been used to steer and promote chemical reactions towards desired products in wet chemical synthesis. However, similar protocols have not been adopted for the on-surface synthesis on solid substrates due to the complexity of reaction processes. Recent advances in the sub-molecular resolution with scanning probe microscopy allow us to capture on-surface reaction pathways and to gain substantial insights into the role of strain in chemical reactions. The primary focus of this review is to highlight the recent findings on strain-induced on-surface reactions. Such substrate-induced processes can be applied to alter the chemical reactivity and to drive on-surface chemical reactions in different manners, which provides a promising alternative approach for on-surface synthesis. This review aims to shed light on the utilization of substrate-induced strain for on-surface transformation and synthesis of atomically-precise novel functional nanomaterials.

中文翻译：

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基质诱导的应变用于表面转化和合成

长期以来，分子间应变一直用于引导和促进化学反应向湿法化学合成中的所需产物发展。但是，由于反应过程的复杂性，尚未在固体基质上进行表面合成的类似方案。扫描探针显微镜在亚分子分辨率上的最新进展使我们能够捕获表面反应途径，并获得对菌株在化学反应中作用的实质性了解。这篇综述的主要重点是强调关于应变诱导的表面反应的最新发现。此类底物诱导的过程可以应用于改变化学反应性并以不同方式驱动表面化学反应，这为表面合成提供了一种有希望的替代方法。