Diverse P,N-phosphine ligands reported to date have performed exceptionally well as auxiliary ligands in organometallic catalysis. Phosphines bearing 2-pyridyl moieties prominently feature in literature as compared to phosphines with five-membered N-heterocycles. This discussion seeks to paint a broad picture and consolidate different synthetic protocols and techniques for N-heterocyclic phosphine motifs. The introduction provides an account of P,N-phosphine ligands, and their structural and coordination benefits from combining heteroatoms with different basicity in one ligand. The body discusses the synthetic protocols which focus on P–C, P–N-bond formation, substrate and nucleophile types and different N-heterocycle construction strategies. Selected references are given in relation to the applications of the ligands.

中文翻译：

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P，N-杂环膦配体的结构与合成

迄今报道的各种P，N-膦配体在有机金属催化中作为辅助配体表现出色。与具有五元N-杂环的膦相比，具有2-吡啶基部分的膦在文献中具有显着特征。该讨论旨在描绘一幅广阔的画面，并巩固N杂环膦基序的不同合成方案和技术。引言提供了对P，N-膦配体的描述，以及它们在结构和配位方面的好处，是将一种具有不同碱性的杂原子结合到一个配体中。该机构讨论了合成方案，这些方案集中在P–C，P–N键的形成，底物和亲核试剂类型以及不同的N-杂环构建策略上。关于配体的应用给出了选择的参考文献。