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Precision health: A pragmatic approach to understanding and addressing key factors in autoimmune diseases.
Autoimmunity Reviews ( IF 13.6 ) Pub Date : 2020-03-12 , DOI: 10.1016/j.autrev.2020.102508
Karsten Conrad 1 , Yehuda Shoenfeld 2 , Marvin J Fritzler 3
Affiliation  

The past decade has witnessed a significant paradigm shift in the clinical approach to autoimmune diseases, lead primarily by initiatives in precision medicine, precision health and precision public health initiatives. An understanding and pragmatic implementation of these approaches require an understanding of the drivers, gaps and limitations of precision medicine. Gaining the trust of the public and patients is paramount but understanding that technologies such as artificial intelligences and machine learning still require context that can only be provided by human input or what is called augmented machine learning. The role of genomics, the microbiome and proteomics, such as autoantibody testing, requires continuing refinement through research and pragmatic approaches to their use in applied precision medicine.

中文翻译:

精准健康:一种实用的方法,用于了解和解决自身免疫性疾病的关键因素。

在过去的十年中,自身免疫性疾病的临床方法发生了重大的模式转变,主要由精准医学,精准健康和精准公共健康举措引领。对这些方法的理解和务实的实现要求对精密医学的驱动力,差距和局限性有一个了解。获得公众和患者的信任是最重要的,但要理解,诸如人工智能和机器学习之类的技术仍然需要只能由人工输入或所谓的增强型机器学习提供的上下文。基因组学,微生物组和蛋白质组学的作用,例如自身抗体检测,需要通过研究和实用方法不断完善,以应用于精密医学。
更新日期:2020-04-20
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