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Plasma proteomic signature of the risk of developing mobility disability: A 9-year follow-up.
Aging Cell ( IF 7.8 ) Pub Date : 2020-03-10 , DOI: 10.1111/acel.13132
Yusuke Osawa 1 , Richard D Semba 2 , Giovanna Fantoni 3 , Julián Candia 4 , Angélique Biancotto 5 , Toshiko Tanaka 1 , Stefania Bandinelli 6 , Luigi Ferrucci 1
Affiliation  

Mobility disability is a powerful indicator of poor health in older adults. The biological and pathophysiological mechanism underlying the development of mobility disability remains unknown. This study conducted a data‐driven discovery phase investigation to identify plasma proteins that predict the incidence of mobility disability in community‐dwelling older adults without mobility disability at baseline.

中文翻译:

血浆蛋白质组学特征表明行动不便的风险:9年的随访。

行动不便是老年人健康状况不佳的有力指标。导致行动不便的潜在生物学和病理生理机制仍然未知。这项研究进行了数据驱动的发现阶段调查,以鉴定血浆蛋白,这些血浆蛋白可预测基线时没有行动障碍的社区居民老年人的行动障碍的发生率。
更新日期:2020-03-10
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