The development of Ni-catalyzed C-N cross-couplings of sulfonamides with (hetero)aryl chlorides is reported. These transformations, which were previously achievable only with Pd catalysis, are enabled by use of air-stable (L)NiCl(o-tol) pre-catalysts (L=PhPAd-DalPhos and PAd2-DalPhos), without photocatalysis. The collective scope of (pseudo)halide electrophiles (X=Cl, Br, I, OTs, and OC(O)NEt2 ) demonstrated herein is unprecedented for any reported catalyst system for sulfonamide C-N cross-coupling (Pd, Cu, Ni, or other). Preliminary competition experiments and relevant coordination chemistry studies are also presented.

中文翻译：

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镍催化的磺酰胺与（杂）芳基氯化物的交叉偶联。

据报道，Ni催化的磺酰胺与（杂）芳基氯化物的CN交叉偶联的发展。这些转变以前只能通过Pd催化才能实现，可以通过使用空气稳定的（L）NiCl（o-tol）预催化剂（L = PhPAd-DalPhos和PAd2-DalPhos）来实现，而无需进行光催化。对于任何已报道的磺酰胺CN交叉偶联催化剂体系（Pd，Cu，Ni或O），本文证明的（伪）卤化亲电试剂（X = Cl，Br，I，OTs和OC（O）NEt2）的总体范围是前所未有的。其他）。还提供了初步竞争实验和相关的配位化学研究。