The prevalence and mortality risk of depression in people with human immunodeficiency virus (HIV) infection receiving antiretroviral therapy (ART) is higher than in the general population, yet biomarkers for therapeutic targeting are unknown. In the current study, we aimed to identify plasma metabolites associated with depressive symptoms in people with HIV receiving ART.

中文翻译：

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低神经活性类固醇在抑制性抗逆转录病毒治疗中识别出患有人类免疫缺陷病毒的成人抑郁症的生物学亚型

在接受抗逆转录病毒治疗 (ART) 的人类免疫缺陷病毒 (HIV) 感染者中，抑郁症的患病率和死亡风险高于普通人群，但治疗靶向的生物标志物尚不清楚。在目前的研究中，我们旨在确定与接受 ART 的 HIV 感染者的抑郁症状相关的血浆代谢物。