The recognition that new cancer drugs can be truly tumour-agnostic based on mechanism-of-action is important for paediatric cancers, where access to novel targeted therapies developed for adult indications has sometimes been problematic. The recently approved drug larotrectinib is an excellent case study of the development of a tumour-agnostic drug relevant to children.

中文翻译：

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小儿癌症中与肿瘤无关的药物。

基于作用机理，新的癌症药物可以真正实现肿瘤不可识别的认识对于小儿癌症很重要，因为在小儿癌症中，获取针对成人适应症开发的新型靶向疗法有时会遇到问题。最近批准的药物larotrectinib是开发与儿童有关的肿瘤不可知药物的出色案例研究。