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A dual-brain approach for understanding the neuralmechanisms that underlie the comforting effects of social touch.
Cortex ( IF 3.6 ) Pub Date : 2020-03-11 , DOI: 10.1016/j.cortex.2020.01.028
Adi Korisky 1 , Naomi I Eisenberger 2 , Michael Nevat 3 , Irit Weissman-Fogel 4 , Simone G Shamay-Tsoory 3
Affiliation  

Across different cultures, social touch is used to alleviate distress. Here we adopt a dual-brain approach with fMRI to examine whether social touch involves similar activations between the suffering 'target' and the empathizer in brain regions related to emotional sharing such as the observation-execution (mirror) network. To inspect the neural underpinnings of the effects of social touch on pain, we scanned romantic couples during a task that required one partner (the empathizer) to hold the target's hand as the latter experienced painful thermal stimulation. Empathizers and target participants were scanned sequentially, in two counterbalanced phases. Results revealed that hand-holding reduced the pain of the target participant, compared to the severity of pain in a control condition (holding a rubber ball). Importantly, during social touch we found striking shared activations between the target and empathizer in the inferior parietal lobule (IPL), a region related to the observation-execution network. The brain-to-brain analysis further revealed a positive correlation of IPL activation levels between the target and the empathizer. Finally, psychophysiological interaction (PPI) analysis in the target showed that the IPL activity during social touch was positively coupled with activity in the dorsomedial prefrontal cortex, a region that has been implicated in emotion regulation, suggesting that the interaction between the observation-execution network and emotion regulation network may contribute to pain reduction during social touch.

中文翻译:

一种双脑方法,用于理解社会交往的安慰作用所基于的神经机制。

在不同的文化中,社交触觉可以减轻痛苦。在这里,我们采用具有fMRI的双脑方法来检查社交接触是否在受痛苦的“目标”和同情者(例如观察执行网络)的大脑区域中的移情者之间进行了类似的激活。为了检查社交触摸对疼痛影响的神经基础,我们在一项任务中扫描了浪漫情侣,该任务需要一个伴侣(移情者)握住目标的手,因为后者经历了痛苦的热刺激。移情者和目标参与者在两个平衡阶段被依次扫描。结果显示,与对照情况下(握住橡皮球)的疼痛严重程度相比,手握可减轻目标参与者的疼痛。重要的,在社交活动中,我们发现下顶小叶(IPL)(与观察执行网络相关的区域)中的目标和移情者之间共有共同的激活。脑到脑的分析进一步揭示了目标和移情者之间IPL激活水平的正相关。最后,对目标的心理生理交互作用(PPI)分析表明,社交接触过程中的IPL活动与背侧前额叶皮层(一个涉及情绪调节的区域)的活动呈正相关,这表明观察与执行网络之间的交互作用情绪调节网络可能有助于减轻社交接触中的疼痛。与观察执行网络有关的区域。脑到脑的分析进一步揭示了目标和移情者之间IPL激活水平的正相关。最后,对目标的心理生理交互作用(PPI)分析表明,社交接触过程中的IPL活动与背侧前额叶皮层(一个涉及情绪调节的区域)的活动呈正相关,这表明观察与执行网络之间的交互作用情绪调节网络可能有助于减轻社交接触中的疼痛。与观察执行网络有关的区域。脑到脑的分析进一步揭示了目标和移情者之间IPL激活水平的正相关。最后,对目标的心理生理交互作用(PPI)分析表明,社交接触过程中的IPL活动与背侧前额叶皮层(一个涉及情绪调节的区域)的活动呈正相关,这表明观察与执行网络之间的交互作用情绪调节网络可能有助于减轻社交接触中的疼痛。
更新日期:2020-04-13
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