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Are You There? Genetic Variation Impacts Long-Distance Connections in Diabetes
Trends in Immunology ( IF 16.8 ) Pub Date : 2020-03-10 , DOI: 10.1016/j.it.2020.02.006
Hannah C. Walter , Amy S. Weinmann

A new study by Fasolino et al. defines how genetic variation in a mouse model of type 1 diabetes mellitus (T1DM) affects long-distance genomic interactions. The research has widespread implications for understanding how genetic diversity impacts disease susceptibility, and raises important concepts about mechanisms that can be influenced by genetic diversity between individuals.



中文翻译:

你在那里吗?遗传变异影响糖尿病的远距离连接

Fasolino等人的一项新研究定义了1型糖尿病(T1DM)小鼠模型中的遗传变异如何影响长距离基因组相互作用。这项研究对于理解遗传多样性如何影响疾病易感性具有广泛的意义,并提出了有关可能受个体间遗传多样性影响的机制的重要概念。

更新日期:2020-03-12
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