Two known briarane diterpenoids, excavatolide C (1) and briacavatolide C (5), along with three new polyoxygenated analogues, briarenols F–H (2–4), have been isolated from the supercritical CO₂ extraction of an octocoral identified as Briareum excavatum. The absolute configuration of 1 was determined by a single-crystal X-ray diffraction analysis for the first time and the structures of 2–5 were established by spectroscopic methods. Bioactivity study showed that briaranes 1, 4 and 5 showed inhibition effects on iNOS release from RAW264.7.

中文翻译：

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Briarenols F-H：由octocoral产生新多氧briarane二萜类化合物Briareum excavatum

两个已知briarane二萜类化合物，excavatolide C（1）和briacavatolide C（5）中，用三种新的多氧类似物一起briarenols F-H（2 - 4），已经从超临界CO分离₂萃取识别为octocoral的Briareum excavatum。的绝对构型1被首次单晶X射线衍射分析和结构确定的2 - 5通过光谱方法建立的。生物活性研究表明，briaranes 1，4和5 对iNOS从RAW264.7释放具有抑制作用。