Selective production of amines using non-noble-based catalysts is of crucial industrial importance. The amination of cyclohexanol (CHOL) was performed in a fixed-bed reactor, using NH₃ as an aminating agent in the presence of H₂, over a commercial Ni-based catalyst, yielding cyclohexylamine (CHA). Higher boiling-point byproducts or heavy ends (HEs) were also detected. Prior to reaction, the catalyst pretreatment temperature was optimized, because at high reduction temperatures, CHOL conversion and product yields decreased because of Ni sintering. A parametric study was then performed, ranging pressure from 1 to 4 barg, temperature from 100 to 200 °C, and the NH₃/H₂/CHOL molar ratio from 1.2:1.2:1 to 3.2:3.2:1. Overall, the obtained results showed that the amination reaction of CHOL is highly temperature-dependent, while pressure slightly affects selectivity. High selectivity toward CHA accompanied by low HE selectivity was obtained, for smoother operating conditions than those previously reported, representing a highly interesting approach to apply at the industrial scale.

中文翻译：

---

商用镍基催化剂上环己醇的胺化反应，第一部分：操作条件的影响

使用基于非贵金属的催化剂选择性生产胺具有至关重要的工业重要性。环己醇（CHOL）的胺化反应是在固定床反应器中，使用NH ₃作为胺化剂，在H ₂的存在下，在市售的Ni基催化剂上进行的，得到环己胺（CHA）。还检测到较高的沸点副产物或重质馏分（HE）。在反应之前，优化了催化剂的预处理温度，因为在高还原温度下，由于Ni的烧结，CHOL转化率和产物产率降低。然后进行参数研究，压力范围为1至4 barg，温度范围为100至200°C，NH ₃ / H ₂/ CHOL摩尔比为1.2：1.2：1至3.2：3.2：1。总的来说，获得的结果表明CHOL的胺化反应高度依赖于温度，而压力对选择性的影响很小。与先前报道的条件相比，在较平稳的操作条件下，获得了对CHA的高选择性和较低的HE选择性，这是在工业规模上应用的一种非常有趣的方法。