With the rise of bacterial infections and antimicrobial resistance, it is important to develop environmentally friendly functional materials and surfaces with efficient bactericidal activity. In this work, nanostructured graphitic carbon nitride (g-C₃N₄) surfaces were fabricated by electrophoresis deposition of mesoporous g-C₃N₄ materials. Efficient bactericidal performance was achieved through the synergistic biophysical interaction of bacterial cells with the nanotopographies and visible light active photocatalytic properties. The nanotopographies of g-C₃N₄ surfaces demonstrated a “contact-killing” efficiency of >90% against Pseudomonas aeruginosa and >80% against Staphylococcus aureus cells. The number of surviving bacteria on the surfaces further decreased remarkably upon illumination using visible light generated by a light-emitting diode lamp with an irradiation intensity of 12.4 mW cm^–2. In total, the number of viable bacteria was reduced by approximately 3 orders of magnitude for P. aeruginosa and 2 orders of magnitude for S. aureus. Our experimental findings provide potential prospects for developing highly efficient photocatalytic bactericidal surfaces.

中文翻译：

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具有高效杀菌性能的电泳沉积介孔石墨氮化碳表面

随着细菌感染和抗菌素耐药性的增加，开发具有高效杀菌活性的环保功能材料和表面非常重要。在这项工作中，纳米结构的石墨碳氮化碳（gC ₃ N _{4 ）表面是通过介孔gC 3} N ₄材料的电泳沉积来制造的。通过细菌细胞与纳米形貌和可见光活性光催化特性的协同生物物理相互作用，实现了高效的杀菌性能。gC ₃ N _{4表面的纳米形貌显示对}铜绿假单胞菌的“接触杀灭”效率>90%和 >80% 的金黄色葡萄球菌细胞。^{使用照射强度为 12.4 mW cm -2}的发光二极管灯产生的可见光照射后，表面上存活的细菌数量进一步显着减少。总的来说，铜绿假单胞菌的活细菌数量减少了大约 3 个数量级，金黄色葡萄球菌减少了2 个数量级。我们的实验结果为开发高效的光催化杀菌表面提供了潜在的前景。