Current poly‐l‐lactide acid (PLLA) scaffolds have issues of inadequate mechanical strength leading to thrombosis formation. Designing a novel bioabsorbable PLLA stent with a novel structure and improved mechanical property is urgently needed. In this study, stent structure modification and optimization based on bioresorbable vascular scaffold Version 1.1 (BVS 1.1, Abbott Laboratories) were conducted. The mechanical property of the redesigned stent was studied using both computerized finite element analysis and experimental mechanical deformation testing, including radial strength (RS), acute recoil (AR), foreshortening (FS), and bending stiffness (BS). The simulated and experimental results showed that the mechanical properties of the modified structure were significantly improved (modified stent vs. BVS 1.1: RS: 2.25 vs. 1.29 N/mm; AR: 3.03 vs. 4.41%; FS: 1.13 vs. 6.89%; BS: 1.49 vs. 0.72 N mm²).

中文翻译：

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具有改善的径向强度和急性回缩率的聚左旋丙交酯冠状动脉支架的结构优化和有限元分析。

目前聚升丙交酯酸 (PLLA) 支架存在机械强度不足导致血栓形成的问题。迫切需要设计一种结构新颖、力学性能提高的新型生物可吸收 PLLA 支架。本研究基于生物可吸收血管支架1.1版（BVS 1.1，雅培实验室）对支架结构进行了修改和优化。使用计算机有限元分析和实验机械变形测试研究了重新设计的支架的机械性能，包括径向强度 (RS)、急性后坐力 (AR)、缩短 (FS) 和弯曲刚度 (BS)。模拟和实验结果表明，改良结构的力学性能得到显着改善（改良支架 vs. BVS 1.1：RS：2.25 vs. 1.29 N/mm；AR：3.03 vs. 4.41%；FS：1。13 对 6.89%；BS：1.49 与 0.72 牛毫米²）。