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Functional comparison of paper-based immunoassays based on antibodies and engineered binding proteins
Analyst ( IF 4.2 ) Pub Date : 2020/03/09 , DOI: 10.1039/d0an00299b
Ki-Joo Sung 1, 2, 3, 4 , Yara Jabbour Al Maalouf 1, 2, 3, 4 , Quinlan R. Johns 1, 2, 3, 4 , Eric A. Miller 1, 2, 3, 4 , Hadley D. Sikes 1, 2, 3, 4, 5
Affiliation  

Binding protein scaffolds, such as rcSso7d, have been investigated for use in diagnostic tests; however, the functional performance of rcSso7d has not yet been studied in comparison to antibodies. Here, we assessed the analyte-binding capabilities of rcSso7d and antibodies on cellulose with samples in buffer and 100% human serum.

中文翻译:

基于抗体和工程结合蛋白的纸质免疫测定的功能比较

已经研究了结合蛋白支架,例如rcSso7d,用于诊断测试。但是,与抗体相比,尚未研究rcSso7d的功能性能。在这里,我们用缓冲液和100%人血清中的样品评估了rcSso7d和纤维素上抗体的分析物结合能力。
更新日期:2020-03-31
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