To demonstrate the long-range effects of CD8+ T cell–secreted interferon-γ on bystander tumor cells, two studies now use mosaic models of antigen loss in tumors combined with intravital imaging. Factors that influence the length scale of diffusible signals could shape disease progression in cancer and autoimmunity.

中文翻译：

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用 IFN-γ 轰炸肿瘤

为了证明 CD8+ T 细胞分泌的干扰素-γ 对旁观者肿瘤细胞的长期影响，现在有两项研究使用肿瘤中抗原丢失的镶嵌模型与活体成像相结合。影响可扩散信号长度尺度的因素可能会影响癌症和自身免疫的疾病进展。