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Clinical impact of FDG PET/CT in alimentary tract malignancies: an updated review.
Abdominal Radiology ( IF 2.4 ) Pub Date : 2020-04-01 , DOI: 10.1007/s00261-020-02447-0
Esma A Akin 1 , Zain N Qazi 1 , Murat Osman 2 , Robert K Zeman 1
Affiliation  

The use of 18F-fluorodeoxyglucose (FDG) positron emission tomography combined with computed tomography (PET/CT) is well established in the evaluation of alimentary tract malignancies. This review of the literature and demonstration of correlative images focuses on the current role of PET/CT in the diagnosis (including pathologic/clinical staging) and post-therapy follow-up of esophageal, gastric, and colorectal cancers. PET/CT provides utility in the management of esophageal cancer, including detection of distant disease prior to resection. In gastric cancer, PET/CT is useful in detecting solid organ metastases and in characterizing responders vs. non-responders after neoadjuvant chemotherapy, the latter of which have poorer overall survival. In patients with GIST tumors, PET/CT also determines response to imatinib therapy with greater expedience as compared to CECT. For colorectal cancer, PET/CT has proven helpful in detecting hepatic and other distant metastases, treatment response, and differentiating post-radiation changes from tumor recurrence. Our review also highlights several pitfalls in PET/CT interpretation of alimentary tract lesions.

中文翻译:

FDG PET / CT在消化道恶性肿瘤中的临床影响:最新综述。

18F-氟脱氧葡萄糖(FDG)正电子发射断层显像结合计算机断层显像(PET / CT)在消化道恶性肿瘤评估中已得到公认。这篇文献综述和相关图像的演示集中于PET / CT在食管癌,胃癌和大肠癌的诊断(包括病理/临床分期)和治疗后随访中的当前作用。PET / CT可用于食管癌的治疗,包括在切除之前检测远处的疾病。在胃癌中,PET / CT可用于检测实体器官转移,以及表征新辅助化疗后的反应者与非反应者,后者的总生存期较差。在患有GIST肿瘤的患者中,与CECT相比,PET / CT还可以更快地确定对伊马替尼治疗的反应。对于结直肠癌,PET / CT已被证明有助于检测肝和其他远处转移,治疗反应以及区分放射后的变化与肿瘤的复发。我们的评论还突出了消化道病变的PET / CT解释中的一些陷阱。
更新日期:2020-03-10
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