Neurymenolides, α-pyrone macrolides isolated from the Fijian red alga Neurymenia fraxinifolia, are anti-methicillin-resistant Staphylococcus aureus and anti-vancomycin-resistant Enterococcus faecium compounds. In this study, the macrocyclic core of neurymenolide A was constructed in an enantioselective manner by employing Claisen rearrangement as the key step.

中文翻译：

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神经烯内酯对映体选择性合成的研究A：通过克莱森重排构建大环核

Neurymenolides，从斐济红藻Neurymenia fraxinifolia分离得到的α-吡喃酮类大环内酯，是抗甲氧西林的金黄色葡萄球菌和抗万古霉素的粪肠球菌化合物。在这项研究中，以克莱森重排为关键步骤，以对映选择性的方式构建了神经烯内酯A的大环核。