Biomolecules, especially proteins and nucleic acids, have been widely studied to develop biochips for various applications in scientific fields ranging from bioelectronics to stem cell research. However, restrictions exist due to the inherent characteristics of biomolecules, such as instability and the constraint of granting the functionality to the biochip. Introduction of functional nanomaterials, recently being researched and developed, to biomolecules have been widely researched to develop the nanobiohybrid materials because such materials have the potential to enhance and extend the function of biomolecules on a biochip. The potential for applying nanobiohybrid materials is especially high in the field of bioelectronics. Research in bioelectronics is aimed at realizing electronic functions using the inherent properties of biomolecules. To achieve this, various biomolecules possessing unique properties have been combined with novel nanomaterials to develop bioelectronic devices such as highly sensitive electrochemical‐based bioelectronic sensing platforms, logic gates, and biocomputing systems. In this review, recently reported bioelectronic devices based on nanobiohybrid materials are discussed. The authors believe that this review will suggest innovative and creative directions to develop the next generation of multifunctional bioelectronic devices.

中文翻译：

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基于纳米生物混合材料的生物电子设备。

已经对生物分子，尤其是蛋白质和核酸进行了广泛的研究，以开发生物芯片，以用于从生物电子学到干细胞研究等科学领域的各种应用。然而，由于生物分子的固有特性，例如不稳定性和将功能性授予生物芯片的限制，存在限制。近年来，已经对功能分子纳米材料引入生物分子进行了广泛的研究，以开发纳米生物杂交材料，因为这种材料具有增强和扩展生物芯片在生物芯片上的功能的潜力。在生物电子领域，应用纳米生物混合材料的潜力特别高。生物电子学的研究旨在利用生物分子的固有特性实现电子功能。为了实现这一目标，具有独特性能的各种生物分子已经与新型纳米材料相结合，以开发生物电子设备，例如基于电化学的高灵敏度生物电子传感平台，逻辑门和生物计算系统。在这篇综述中，讨论了最近报道的基于纳米生物混合材料的生物电子设备。作者认为，这篇评论将为开发下一代多功能生物电子设备提出创新和创造性的方向。最近讨论了基于纳米生物混合材料的生物电子设备。作者认为，这篇评论将为开发下一代多功能生物电子设备提出创新和创造性的方向。最近讨论了基于纳米生物混合材料的生物电子设备。作者认为，这篇评论将为开发下一代多功能生物电子设备提出创新和创造性的方向。