A rational design of chiroptical active materials from a multi-component co-assembly remains a great challenge due to the spontaneous pathway competition and complexity. In this study, we report a modularized, ternary component co-assembly system constituted by two N-terminated aromatic glutamic amino acids and an imidazole-based binder, which demonstrate mutual binding behaviors via aromatic interactions and complementary H-bonds that allow for flexible manipulation of the chiroptical activities, including circularly polarized light absorbance and luminescence. Through a modular combination, we synthesized up to six self-assembled aggregates with distinct chiroptical activities, showing chirality emergence, transfer, amplification and inversion behaviors. The modular molecular self-assembly protocol provides an alternative route to the noncovalent synthesis of chiroptical active materials with high throughput efficacy.

中文翻译：

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具有灵活定制的按摩特性的三元模块化分子共组装

由于自发途径竞争和复杂性，从多组分共组装物中合理设计按摩疗法活性材料仍然是巨大的挑战。在这项研究中，我们报告了一个模块化的三元组分共组装系统，该系统由两个N末端的芳香族谷氨酸和一个咪唑基的粘合剂组成，它们通过芳香族相互作用和互补的H键，可以灵活地控制按摩疗法的活动，包括圆偏振光的吸收和发光。通过模块化组合，我们合成了多达六个具有不同手性活性的自组装聚集体，显示出手性的出现，转移，扩增和倒置行为。模块化分子自组装方案为非共价合成手性活性物质提供了另一种途径，具有高通量功效。