New research suggests that cytotoxic T cells are dominant in the lesional skin of patients with early diffuse cutaneous systemic sclerosis (SSc) and contribute to vasculopathy and tissue fibrosis. Could therapeutic strategies that prevent T cell activation and cytotoxicity therefore present an option to potentially halt progression of SSc?

中文翻译：

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SSc皮肤病变中的T细胞：了解您的敌人。

新研究表明，细胞毒性T细胞在早期弥漫性皮肤系统性硬化症（SSc）患者的病变皮肤中占主导地位，并导致血管病变和组织纤维化。因此，预防T细胞活化和细胞毒性的治疗策略是否可能提供阻止SSc进程的选择？