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“Development and application of analytical detection techniques for droplet-based microfluidics”-A Review
Analytica Chimica Acta ( IF 6.2 ) Pub Date : 2020-05-01 , DOI: 10.1016/j.aca.2020.03.011
Wen-Wen Liu 1 , Ying Zhu 2
Affiliation  

Droplet-based microfluidics has emerged as a powerful platform for high-throughput and low-volume analysis and screening. At present, droplet-based microfluidics is transitioning from the proof-of-concept stage to real-world applications. During this process, analytical detection techniques play indispensable roles for successfully implementing droplet-based chemical or biological assays. In this review, we provide an overview of recent developments in analytical techniques for droplet analysis and elucidate the advantages and limitations of each technique. We cover the majority of technology categories, including optical detection, electrical detection, mass spectrometry, and nuclear magnetic resonance spectroscopy. Additionally, we highlight new research areas that have been enabled by these technical advances. Finally, we provide perspectives on both future technological directions and potential enabling applications.

中文翻译:

“基于液滴的微流体分析检测技术的发展与应用”——综述

基于液滴的微流体已成为高通量和低体积分析和筛选的强大平台。目前,基于液滴的微流体正在从概念验证阶段过渡到实际应用。在此过程中,分析检测技术对于成功实施基于液滴的化学或生物测定起着不可或缺的作用。在这篇综述中,我们概述了液滴分析分析技术的最新发展,并阐明了每种技术的优点和局限性。我们涵盖了大多数技术类别,包括光学检测、电检测、质谱和核磁共振光谱。此外,我们重点介绍了这些技术进步带来的新研究领域。最后,
更新日期:2020-05-01
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