Abstract Hafnium Oxide nanoparticles have been synthesized by precipitation method and analyzed for its structural, Morphological and dosimetric properties. The structural and morphological properties are examined by utilizing XRD and FESEM. The investigation of dosimetric parameter has been carried out with the usage of annealing and thermal quenching of HfO2 NPs. The monoclinic phase arrangements of HfO2 with space group [P21/c] were well characterized by retiveld refinement and PXRD pattern. From FESEM and EDS studies it is observed that the estimated size of NPs is 58 nm, spherical in shape and the Hf/O proportion are found to be 0.4211, The heating rate of HfO2 are Optimized by studying the glow curve for various heating rate and Optimized at 10 °C/s and the annealing temperature has been carried out for 10 °C/s heating rate by varying the temperature and time and optimized to 300 °C at 30 min. The dosimetric parameters such as ECF, CV, Batch homogeneity, photo dose-linearity and reproducibility were studied using 60Co beam. Hence the observed results clearly indicates that the HfO2 NPs can be utilized as dosimetric material in the application of Radiotherapy and it can be effectively used in Radiation dosimetry especially for Neutron dosimetry.

中文翻译：

---

临床 60Co 束中 HfO2 NPs 的结构、形态和剂量学参数分析

摘要 通过沉淀法合成了氧化铪纳米颗粒，并对其结构、形态和剂量学特性进行了分析。通过使用 XRD 和 FESEM 检查结构和形态特性。已经使用 HfO2 NPs 的退火和热淬火进行了剂量学参数的研究。具有空间群 [P21/c] 的 HfO2 的单斜相排列通过 retiveld 细化和 PXRD 图案得到了很好的表征。从 FESEM 和 EDS 研究中观察到，NPs 的估计尺寸为 58 nm，呈球形，Hf/O 比例为 0.4211，HfO2 的加热速率通过研究不同加热速率的辉光曲线进行优化，优化为 10°C/s，退火温度已通过改变温度和时间进行 10°C/s 加热速率并优化为 300 °C 时 30 分钟。使用 60Co 光束研究了剂量学参数，例如 ECF、CV、批次均匀性、光剂量线性和再现性。因此，观察结果清楚地表明，HfO2 NPs 可以用作放射治疗应用中的剂量学材料，并且可以有效地用于辐射剂量学，尤其是中子剂量学。