Three new diterpenoids, euphstrachenols A–C (1, 2, and 11), together with nineteen known analogues were isolated from the roots of Euphorbia stracheyi. Compounds 1 and 2 were lathyrane-type diterpenoids with a decadienoyl acidic moiety. Compound 11 was an ingenane-type diterpenoid with a deca-2′′E,4′′E,6′′E-trien-1-one moiety. Their structures were elucidated by comprehensive spectroscopic analyses. All the isolated compounds were evaluated in vitro for their cytotoxic activity against four human cancer cell lines and a murine cell line, and compounds 1, 2, 4, 5, 7, 9, and 11–14 exhibited moderate cytotoxicity against MV4-11 cell line with IC₅₀ values from 3.48 to 30.02 μM.

三个新的二萜类化合物，euphstrachenols A-C（1，2，和11），加上19个已知类似物从根部分离大戟stracheyi。化合物1和2是具有癸二烯酰基酸性部分的Lathyrane型二萜。化合物11是一种ingenane型二萜与癸2'' ë，4'' ë，6'' ë三烯-1-酮部分。通过全面的光谱分析阐明了它们的结构。在体外评估所有分离出的化合物对四种人类癌细胞系和鼠类细胞系的细胞毒活性，以及1，2，4，5，7，9，和11 - 14表现出适度的细胞毒性对MV4-11细胞系IC _50个从3.48值30.02 μ M.