By choosing different phosphine ligands, nickel-catalyzed selective alkylation and reduction of allylic alcohols with alkyl Grignard reagents were performed. The reaction using Ni(dppe)Cl₂ as the catalyst resulted in the cross-coupling of allylic alcohols with primary alkyl Grignard reagents and cyclopropylmagnesium bromide. The reaction catalyzed by the combination of Ni(PCy₃)₂Cl₂ and dcype led to the reduction of allylic alcohols. Secondary alkyl Grignard reagents except cyclopropylmagnesium bromide always led to reduction of allylic alcohols using either Ni(dppe)Cl₂ or Ni(PCy₃)₂Cl₂/dcype as the catalyst. In the reductive reaction β-H-containing alkyl Grignard reagents were required.

中文翻译：

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镍催化烷基化或烷基格氏试剂还原烯丙醇

通过选择不同的膦配体，进行了镍催化的选择性烷基化反应和用烷基格氏试剂还原烯丙基醇。使用Ni（dppe）Cl ₂作为催化剂的反应导致烯丙基醇与伯烷基格氏试剂和环丙基溴化镁的交叉偶联。Ni（PCy ₃）₂ Cl ₂和dcype的组合催化的反应导致烯丙基醇的还原。除环丙基溴化镁外，仲烷基格氏试剂总是使用Ni（dppe）Cl ₂或Ni（PCy ₃）₂ Cl ₂导致烯丙基醇的还原/ dcype作为催化剂。在还原反应中，需要含β-H的烷基格氏试剂。