Associations between obesity and physical inactivity are bi-directional. Both are associated with physical functioning (PF, ability to perform physical tasks of daily living) but whether obesity influences PF via inactivity is unknown. We investigated whether mid-adult obesity trajectories were associated with subsequent PF and mediated by inactivity.

中文翻译：

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在两个英国出生队列中，成年人肥胖和中年人的身体机能：研究身体不活动的中介作用。

肥胖与缺乏运动之间的关联是双向的。两者都与身体机能（PF，执行日常身体任务的能力）有关，但肥胖是否会因不运动而影响PF尚不清楚。我们调查了中年肥胖的轨迹是否与随后的PF相关并由不活动介导。