Abstract

Although hopeite bioceramic coatings have already proven effective for achieving better osseointegration and antibacterial character, but the detachment of hopeite coatings during implanting of coated implants can negatively affect the hopeite bioactivity in the physiological environment. To overcome this issue, the present research work proposes a new process route of laser rapid manufacturing (LRM) for depositing hopeite coatings with the metallurgical bond. Microstructure, phase composition, microhardness, antibacterial efficacy, and bioactivity were evaluated using scanning electron microscope, X-ray diffraction, Vickers microhardness tester, fluorescence-activated cell sorting technique, simulated body fluid immersion test respectively. The promising results obtained from these characterizations and testing establishes a new process route LRM as an effective alternative to deposit multifunctional hopeite coatings on metallic prosthetic–orthopedic implants.

Graphic Abstract

摘要

尽管已经证明了希望石生物陶瓷涂层对于实现更好的骨整合和抗菌特性是有效的，但是在涂覆的植入物的植入过程中，希望石涂层的脱离会负面影响在生理环境中的希望石生物活性。为了克服这个问题，本研究工作提出了一种新的激光快速制造（LRM）工艺路线，该路线用于沉积具有冶金结合物的希望石涂层。分别用扫描电子显微镜，X射线衍射，维氏显微硬度测试仪，荧光激活细胞分选技术，模拟体液浸没试验评估了显微组织，相组成，显微硬度，抗菌功效和生物活性。

图形摘要